Intractable Rare Dis Res. 2013;2(2):51-54. (DOI: 10.5582/irdr.2013.v2.2.51)

Melorheostosis and a review of the literature in China.

Zhang C, Dai WD, Yang Y, Tang Q, Yao ZJ


Melorheostosis is an uncommon, non-genetic, non-developmental, sclerosing dysplasia of bone and adjacent soft tissues, with deformity of the extremity, pain, limb stiffness and limitation of motion. The characteristic radiographic appearance consists of irregular hyperostotic changes of the cortex resembling melted wax dripping down the side of a candle. In this review, clinical characteristics of Melorheostosis are discussed and reports in the Chinese literature are summarized.

KEYWORDS: Melorheostosis, sclerosing bone dysplasia, developmental anomalies, bone sclerosis, China

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