Intractable Rare Dis Res. 2012;1(4):167-169. (DOI: 10.5582/irdr.2012.v1.4.167)
Henoch-Schönlein purpura associated with a neuroblastoma: Report of one case and a review of the literature.
Dong QL, Cao SS, Zhang HW, Geng H
Malignancies such as solid tumors and hematologic malignancies can often induce or be associated with Henoch-Schönlein purpura (HSP) in older males but not in children. Described here is the case of a 5-year-old boy who clinically presented with HSP. An imaging study of the abdomen revealed a right retroperitoneal neoplasm that histopathology postoperatively confirmed to be a neuroblastoma. Malignancies are sometimes associated with HSP mostly in older males, though children are affected, albeit rarely. Thus, all patients with HSP must be carefully examined to identify or exclude an underlying disease.